Peptide Research Guides
Deep-dive breakdowns of every major research peptide — mechanisms, dosages, side effects, and clinical evidence.
AOD-9604
An evidence-first look at AOD-9604 — the GH fragment studied for fat loss. Clinical trial results, mechanism of action, safety data, and an honest assessment of efficacy.
BPC-157
An evidence-first review of BPC-157 research — preclinical findings on tissue repair, gut protection, and wound healing, with honest assessment of what is and isn't proven.
CJC-1295
An evidence-first review of CJC-1295, covering how it differs from native GHRH, DAC vs no-DAC variants, clinical trial data, and what the research shows about GH stimulation.
DSIP (Delta Sleep-Inducing Peptide)
An evidence-based review of DSIP — the nonapeptide studied for delta wave sleep enhancement, stress hormone regulation, and neuroendocrine modulation. What the data shows and what remains unknown.
Epithalon (Epitalon)
An evidence-based review of Epithalon — the tetrapeptide studied for telomerase activation, melatonin restoration, and lifespan extension. What the data supports and where it falls short.
FOXO4-DRI
An evidence-based review of FOXO4-DRI — research on senescent cell targeting, the p53/FOXO4 interaction, and aging, with honest evidence assessment.
GHK-Cu (Copper Peptide)
An evidence-based review of GHK-Cu — the naturally occurring copper tripeptide studied for wound healing, skin aging, and gene expression modulation. What the research shows.
GHRP-2
An evidence-based review of GHRP-2 — clinical data on growth hormone release, comparisons to GHRP-6 and ipamorelin, and safety considerations.
GHRP-6
An evidence-based review of GHRP-6, covering research on growth hormone secretion, appetite stimulation, and how it compares to newer GH secretagogues.
Hexarelin
An evidence-based review of hexarelin, covering research on growth hormone release, cardiac effects, desensitization concerns, and comparisons to other GHRPs.
Ipamorelin
An evidence-first review of ipamorelin, covering its selectivity compared to other GHRPs, what clinical and preclinical research has demonstrated, and what remains unknown.
Kisspeptin-10
An evidence-based review of Kisspeptin-10 — the neuropeptide that regulates the HPG axis. Clinical research on LH, testosterone, fertility applications, and practical limitations.
KPV
An evidence-based review of KPV peptide — research on anti-inflammatory effects, gut health, NF-κB inhibition, and antimicrobial activity.
LL-37
An evidence-based review of LL-37 (cathelicidin) — research on antimicrobial activity, immune modulation, wound healing, and safety considerations.
Melanotan II (MT-2)
An evidence-first review of Melanotan II (MT-2) — the synthetic melanocortin peptide studied for tanning, sexual function, and appetite. Mechanism of action, clinical data, adverse effects, and regulatory status.
MK-677 (Ibutamoren)
An evidence-based review of MK-677 (ibutamoren) — clinical data on growth hormone secretion, body composition, sleep, and safety considerations.
MOTS-c
An evidence-based review of MOTS-c — research on metabolic regulation, exercise mimicry, AMPK activation, and aging, with honest evidence assessment.
PT-141 (Bremelanotide)
An evidence-based review of PT-141 (bremelanotide/Vyleesi) — the FDA-approved melanocortin receptor agonist studied for sexual desire. Clinical trial data, mechanism, and side effects.
Selank
An evidence-based review of Selank — the tuftsin-derived heptapeptide studied for anxiolytic and nootropic effects. Russian clinical data, mechanism of action, and what is known.
Semaglutide
A comprehensive, evidence-first review of semaglutide (Ozempic/Wegovy) — clinical trial data on weight loss and cardiovascular outcomes, mechanism of action, side effects, and practical considerations.
Semax
An evidence-based review of Semax — the synthetic ACTH(4-10) fragment studied for cognitive enhancement and neuroprotection. Russian clinical data, mechanisms, and honest limitations.
Sermorelin
An evidence-first review of sermorelin — the formerly FDA-approved GHRH analog. Clinical history, mechanism, how it compares to CJC-1295 and tesamorelin, and what the research supports.
TB-500 (Thymosin Beta-4)
An evidence-first review of TB-500 and thymosin beta-4 — preclinical findings on systemic healing, inflammation, and tissue repair, with an honest look at the state of the evidence.
Tesamorelin
An evidence-first review of tesamorelin (Egrifta) — the only currently FDA-approved GHRH analog. Phase III data on visceral fat reduction, emerging cognitive research, and off-label considerations.
Thymosin Alpha-1
An evidence-based review of thymosin alpha-1 (Zadaxin) — clinical data on immune modulation, hepatitis treatment, and cancer adjunct therapy.
Tirzepatide
An evidence-based review of tirzepatide (Mounjaro/Zepbound), covering clinical trial data on weight loss, diabetes, cardiovascular outcomes, and safety.