Guides
Background reading. The four marked "Start here" explain how evidence is graded on this site; the rest cover specific questions and use cases.
| Guide | Covers | Section | Updated |
|---|---|---|---|
| What Are Peptides? A Clear, Evidence-Based Overview | Peptides are short chains of amino acids, usually 2 to 50, that act as signals in the body. Insulin is one. So are semaglutide, BPC-157, and dozens of research compounds. Here is what they are, what they are not, and how to think about them. | Start here | 2026-09-11 |
| How Peptides Are Studied: Animal Data vs Human Evidence | Most of what you read about peptides comes from rat studies. This guide explains the ladder from a petri dish to a Phase III trial, why so much fails to climb it, and how to tell strong evidence from a hopeful start. | Start here | 2026-09-11 |
| How to Read Peptide Claims Critically | A practical method for checking whether a peptide claim is backed by anything: the red flags, the PubMed search, how to read an abstract, and the four features of a study that decide whether it counts. | Start here | 2026-09-11 |
| Peptide Safety: What's Known, What's Unclear, What's Assumed | For a few peptides the safety data is excellent. For most, it does not exist. Here is which is which, why the source is often the bigger risk than the molecule, and what 'generally well tolerated' actually means. | Start here | 2026-09-11 |
| Best Peptides for Anti-Aging: What the Research Actually Supports | Seven peptides get sold for aging and longevity. One has small human trials as a face cream. The rest have mouse studies, a single lab, or a single paper. Here they are ranked by what the evidence actually shows. | Use-Case Guide | 2026-09-11 |
| Common Misconceptions About Peptides (and Why They Persist) | The eight things people most often get wrong about peptides, from 'they're basically steroids' to 'if it worked in rats it works in me,' each corrected with what the evidence actually shows. | Education | 2026-09-11 |
| GLP-1 Peptides Explained: Semaglutide, Tirzepatide, and the Incretin Revolution | GLP-1 is a gut hormone that tells your brain you are full and your pancreas to release insulin. Semaglutide and tirzepatide are longer-lasting copies of it, with the largest trials of any peptide on this site. | Educational Guide | 2026-09-15 |
| How Peptides Are Administered: Routes, Bioavailability, and Why It Matters | Most peptides are injected under the skin because the stomach digests them. Here is which ones work as nasal sprays, creams, or pills, what bioavailability means, and how to tell whether a capsule can survive digestion. | Education | 2026-09-11 |
| Peptide Stacks: What 'Stacking' Means in Research Context | Stacking is taking two or more peptides together on the theory that they work better combined. One combination has human evidence for that. The rest are untested pairs of compounds that are mostly untested on their own. | Education | 2026-09-11 |
| Peptide Storage, Reconstitution, and Handling: What the Science Says | Peptides ship as freeze-dried powder and are fragile once mixed. How to reconstitute them, how long they keep, what breaks them down, and why sloppy handling turns a potency question into a safety one. | Education | 2026-09-11 |
| Peptides Studied for Fat Loss: An Evidence-Based Comparison (2026) | Two peptides produce large, proven fat loss. One reduces belly fat specifically. The growth hormone peptides do little for fat in trials, and AOD-9604 failed its human trial. Here they are ranked by what the evidence actually shows. | Fat Loss | 2026-09-11 |
| Peptides Studied for Injury Recovery and Healing: An Evidence-Based Comparison (2026) | A comparison of the peptides studied for healing injuries, ranked by how good the evidence is. | Recovery | 2026-09-15 |
| Peptides Studied for Muscle Growth and Recovery: An Evidence-Based Comparison (2026) | Growth hormone peptides raise growth hormone reliably and add about a kilogram of lean mass in the best trial. Healing peptides have rat data. Nothing here rivals training, protein, or testosterone. Ranked by evidence. | Muscle Growth | 2026-09-11 |
| Peptides vs SARMs vs Steroids: Understanding the Differences | Peptides, SARMs, and anabolic steroids get sold by the same vendors and discussed in the same forums, but they work in different ways, carry different risks, and rest on very different amounts of evidence. | Comparison Guide | 2026-09-11 |
| Why Most Peptide Evidence Is Preclinical | Most peptides have animal data and no human trials because trials cost hundreds of millions of dollars and only patent-holders fund them. Natural or off-patent peptides never get tested, and that gap is not going to close on its own. | Education | 2026-09-11 |