Peptides
26 compounds. Each page reports the published research, rates the strongest evidence on a four-step scale, and says plainly what has not been shown.
| Studied for | Route | Status | |||
|---|---|---|---|---|---|
| AOD-9604 Fat Loss Peptide | fat loss in obese mice (strong), weight loss in obese adults (failed Phase IIb), cartilage repair (lab and animal), safety and tolerability in humans | Small human | No coded reports yet | subcutaneous injection (oral in the trials) | Not FDA approved as a drug; GRAS as a food ingredient (2010); sold as a research chemical; prohibited by WADA |
| BPC-157 Healing Peptide | Tendon and muscle healing, Gut protection, Nerve and bone repair | Animal | Mixed 28 reports | subcutaneous injection; oral in gut studies | Research chemical; not approved for human use |
| CJC-1295 Growth Hormone Secretagogue | raising growth hormone and IGF-1, body composition (lean mass, belly fat), growth in GHRH-deficient mice, age-related GH decline (proposed, not trialed) | Small human | No coded reports yet | subcutaneous injection | Not FDA approved; clinical development halted in 2006; sold as a research chemical; prohibited by WADA |
| DSIP (Delta Sleep-Inducing Peptide) Sleep Peptide | chronic insomnia, sleep disturbance in alcohol and benzodiazepine withdrawal, stress hormone (cortisol) regulation, pain (modest, older studies) | Small human | No coded reports yet | subcutaneous injection (intravenous in the original studies) | Not FDA approved; sold as a research chemical; not on the WADA list |
| Epithalon (Epitalon) Anti-Aging Peptide | telomere length in cells, lifespan in mice and flies, melatonin in aged animals and people, retinitis pigmentosa (small human study) | Small human | No coded reports yet | subcutaneous or intramuscular injection | Not FDA approved; sold as a research chemical; not on the WADA list; used in Russia as a peptide bioregulator |
| FOXO4-DRI Senolytic Peptide | clearing senescent cells (cells and mice), reversing signs of aging in old mice, kidney function and fur in aged mice | Animal | No coded reports yet | subcutaneous or intraperitoneal injection (mice) | Not approved anywhere; sold as a research chemical; not on the WADA list |
| GHK-Cu (Copper Peptide) Anti-Aging Peptide | skin aging (topical), wound healing (animals), hair growth (lab), gene expression changes | Small human | No coded reports yet | topical cream or serum (subcutaneous injection in community use) | Sold as a cosmetic ingredient; not FDA approved as a drug; injectable form is a research chemical |
| GHRP-2 Growth Hormone Secretagogue | growth hormone release (single-dose human studies), diagnosing growth hormone deficiency (approved test in Japan), synergy with GHRH-type peptides, appetite (human) | Small human | No coded reports yet | subcutaneous injection (intravenous for the diagnostic test) | Approved in Japan as a diagnostic agent only; not FDA approved; sold as a research chemical; prohibited by WADA |
| GHRP-6 Growth Hormone Secretagogue | growth hormone release (human, single dose), appetite (human), heart protection after injury (animals), wound healing (animals) | Small human | No coded reports yet | subcutaneous injection | Not approved anywhere; sold as a research chemical; prohibited by WADA |
| Hexarelin Growth Hormone Secretagogue | growth hormone release (human, single dose), heart contractility (human, small), desensitization with repeated use (human), cortisol and prolactin response (human) | Small human | No coded reports yet | subcutaneous injection | Not approved anywhere; sold as a research chemical; prohibited by WADA |
| Ipamorelin Growth Hormone Secretagogue | growth hormone release (human, single dose), gut motility after surgery (human Phase II, discontinued), lean mass in growth-hormone-deficient pigs, bone density in rats | Small human | No coded reports yet | subcutaneous injection, 1 to 3 times daily | Not approved anywhere; clinical development discontinued; sold as a research chemical and by compounding pharmacies; prohibited by WADA |
| Kisspeptin-10 Hormonal Peptide | IVF egg maturation, LH and testosterone stimulation, hypothalamic amenorrhea, locating hormone-axis problems | Small human | No coded reports yet | intravenous infusion or subcutaneous injection | Research chemical; not approved in any country; in clinical trials for IVF |
| KPV Anti-Inflammatory Peptide | colitis and gut inflammation (mice), skin inflammation (animals), antimicrobial activity (lab), blocking the NF-κB inflammation switch (cells) | Animal | No coded reports yet | subcutaneous injection; oral capsules (used in the mouse work); topical | Not approved anywhere; sold as a research chemical and by some compounding pharmacies; not on the WADA list |
| LL-37 Antimicrobial Peptide | killing bacteria and fungi (lab), breaking up biofilms (lab), skin wound healing (animals, human tissue), immune signaling (lab and animal) | Animal | No coded reports yet | subcutaneous injection in community use; topical in research | Not approved anywhere; sold as a research chemical; not on the WADA list |
| Melanotan II (MT-2) Melanocortin Peptide | Sunless tanning, Sexual arousal, Appetite suppression | Small human | No coded reports yet | subcutaneous injection | Research chemical; not approved anywhere |
| MK-677 (Ibutamoren) Growth Hormone Secretagogue | growth hormone and IGF-1 in older adults (2-year trial), body composition (modest), deep sleep, bone density (preliminary), recovery after hip fracture | Small human | No coded reports yet | oral, once daily | Not approved anywhere; sold as a research chemical, often shelved with SARMs; prohibited by WADA |
| MOTS-c Mitochondrial Peptide | obesity and insulin resistance (mice), physical performance in old mice, response to exercise (human blood levels), metabolic disease (one small human trial of an analog) | Animal | No coded reports yet | subcutaneous injection | Not approved anywhere; sold as a research chemical; prohibited by WADA as a metabolic modulator |
| PT-141 (Bremelanotide) Melanocortin Peptide | low sexual desire in premenopausal women (approved), erectile dysfunction in men (earlier studies), female arousal disorder (earlier studies) | Clinical trials | No coded reports yet | subcutaneous injection, on demand (nasal spray in early studies) | FDA approved (Vyleesi) for premenopausal women with HSDD; prescription only; off-label in men; sold as a research chemical; not on the WADA list |
| Selank Nootropic Peptide | generalized anxiety disorder (small Russian trials), anxiety with cognitive complaints, BDNF and memory in rats, immune modulation (lab) | Small human | No coded reports yet | nasal spray (subcutaneous injection in community use) | Approved in Russia as a prescription nasal spray; not FDA approved; sold as a research chemical elsewhere; not on the WADA list |
| Semaglutide GLP-1 Agonist | chronic weight management, type 2 diabetes, heart attack and stroke prevention, kidney disease, sleep apnea, fatty liver (ongoing or recent trials) | Clinical trials | No coded reports yet | subcutaneous injection weekly (Ozempic, Wegovy); daily oral tablet (Rybelsus) | FDA approved; prescription only; compounded versions restricted by the FDA; not on the WADA list |
| Semax Nootropic Peptide | attention and memory, stroke recovery, optic nerve disease, learning in rodents | Small human | No coded reports yet | nasal spray (subcutaneous injection in community use) | Approved in Russia as a prescription nasal spray; not FDA approved; sold as a research chemical elsewhere |
| Sermorelin Growth Hormone Secretagogue | growth hormone deficiency in children (approved use, withdrawn), growth hormone and IGF-1 in older adults (small studies), deep sleep, diagnosing pituitary function | Clinical trials | No coded reports yet | subcutaneous injection, daily (usually at bedtime) | Formerly FDA approved (Geref, withdrawn 2008); now available only compounded or as a research chemical; prohibited by WADA |
| TB-500 (Thymosin Beta-4) Healing Peptide | wound healing, heart attack recovery, corneal injury and dry eye, brain injury | Animal | No coded reports yet | subcutaneous injection in community use; topical, eye drops, intraperitoneal, and intravenous in studies | Research chemical; not FDA approved; prohibited by WADA |
| Tesamorelin Growth Hormone Secretagogue | visceral (deep belly) fat in HIV lipodystrophy, liver fat in HIV, memory and executive function in older adults (one trial), age-related belly fat (off-label, untested) | Clinical trials | No coded reports yet | subcutaneous injection, daily | FDA approved (Egrifta) for HIV-associated lipodystrophy; prescription only; off-label use legal; prohibited by WADA |
| Thymosin Alpha-1 Immune Modulator | chronic hepatitis B (approved abroad), hepatitis C (with interferon), melanoma and other cancers as an adjunct, severe sepsis, vaccine response in older adults | Clinical trials | No coded reports yet | subcutaneous injection, usually twice weekly | Approved in 35+ countries (Zadaxin); not FDA approved; available compounded and as a research chemical in the US; not on the WADA list |
| Tirzepatide GLP-1/GIP Dual Agonist | chronic weight management, type 2 diabetes, obstructive sleep apnea, heart outcomes (trial ongoing) | Clinical trials | No coded reports yet | subcutaneous injection, weekly | FDA approved (Mounjaro, Zepbound); prescription only; compounded versions restricted by the FDA; not on the WADA list |
Evidence scale: Anecdotal, Animal, Small human, Clinical trials. Filled squares mark the strongest evidence available for that peptide. Dashed squares mean the page has not been rated yet. What people say: public forum reports coded one by one (helped, mixed, no effect, bad experience); the bar shows the split and the label is called only once there are at least 8 reports.